The tidal volume fix?

Intraoperative low-tidal-volume ventilation.

Low Tidal Volume Ventilation: Trust but Verify.

Despite affecting an estimated 4 –7% of patients in the ICU and having a high mortality rate, there are currently a limited number of therapeutic options to treat patients with ARDS.1,2 ARMA, the landmark ARDSnet trial in 2000, established the concept of lungprotective ventilation, where subjects with ARDS receiving mechanical ventilation were randomly assigned to a set tidal volume (VT) of eit...

Low-tidal-volume ventilation in the acute respiratory distress syndrome.

Copyright © 2007 Massachusetts Medical Society. A 55-year-old man who is 178 cm tall and weighs 95 kg is hospitalized with community-acquired pneumonia and progressively severe dyspnea. His arterial oxygen saturation while breathing 100% oxygen through a face mask is 76%; a chest radiograph shows diffuse alveolar infiltrates with air bronchograms. He is intubated and receives mechanical ventila...

Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome.

RATIONALE Tidal volume and plateau pressure limitation decreases mortality in acute respiratory distress syndrome. Computed tomography demonstrated a small, normally aerated compartment on the top of poorly aerated and nonaerated compartments that may be hyperinflated by tidal inflation. OBJECTIVES We hypothesized that despite tidal volume and plateau pressure limitation, patients with a larg...

Correlation properties of tidal volume and end-tidal O2 and CO2 concentrations in healthy infants.

We investigated whether breath-to-breath fluctuations in tidal volume (VT) and end-tidal O2 and CO2 exhibit long-range correlations and whether parameters describing the correlations can be used as noninvasive descriptors of control of breathing. We measured VT and end-tidal O2 and CO2 over n = 352 +/- 104 breaths in 26 term, healthy, unsedated infants (mean age +/- SD: 36 +/- 6 days) and calcu...